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Agent Clustering Strategy Based on Metabolic Flux Distribution and Transcriptome Expression for Novel Drug Development

The network module-based method has been used for drug repositioning. The traditional drug repositioning method only uses the gene characteristics of the drug but ignores the drug-triggered metabolic changes. The metabolic network systematically characterizes the connection between genes, proteins,...

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Detalles Bibliográficos
Autores principales:	Ruan, Yao, Chen, Xiao-Hui, Jiang, Feng, Liu, Yan-Guang, Liang, Xiao-Long, Lv, Bo-Min, Zhang, Hong-Yu, Zhang, Qing-Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615746/ https://www.ncbi.nlm.nih.gov/pubmed/34829869 http://dx.doi.org/10.3390/biomedicines9111640

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