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Modification of Glyceraldehyde-3-Phosphate Dehydrogenase with Nitric Oxide: Role in Signal Transduction and Development of Apoptosis

This review focuses on the consequences of GAPDH S-nitrosylation at the catalytic cysteine residue. The widespread hypothesis according to which S-nitrosylation causes a change in GAPDH structure and its subsequent binding to the Siah1 protein is considered in detail. It is assumed that the GAPDH co...

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Detalles Bibliográficos
Autores principales: Muronetz, Vladimir I., Medvedeva, Maria V., Sevostyanova, Irina A., Schmalhausen, Elena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615796/
https://www.ncbi.nlm.nih.gov/pubmed/34827652
http://dx.doi.org/10.3390/biom11111656