Data-Driven Analysis of Fluorination of Ligands of Aminergic G Protein Coupled Receptors

Currently, G protein-coupled receptors are the targets with the highest number of drugs in many therapeutic areas. Fluorination has become a common strategy in designing highly active biological compounds, as evidenced by the steadily increasing number of newly approved fluorine-containing drugs. He...

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Detalles Bibliográficos
Autores principales: Pietruś, Wojciech, Kurczab, Rafał, Stumpfe, Dagmar, Bojarski, Andrzej J., Bajorath, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615825/
https://www.ncbi.nlm.nih.gov/pubmed/34827645
http://dx.doi.org/10.3390/biom11111647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615825/
https://www.ncbi.nlm.nih.gov/pubmed/34827645
http://dx.doi.org/10.3390/biom11111647

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