An Asp to Strike Out Cancer? Therapeutic Possibilities Arising from Aspartate’s Emerging Roles in Cell Proliferation and Survival

A better understanding of the metabolic constraints of a tumor may lead to more effective anticancer treatments. Evidence has emerged in recent years shedding light on a crucial aspartate dependency of many tumor types. As a precursor for nucleotide synthesis, aspartate is indispensable for cell pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Helenius, Iiro Taneli, Madala, Hanumantha Rao, Yeh, Jing-Ruey Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615858/
https://www.ncbi.nlm.nih.gov/pubmed/34827664
http://dx.doi.org/10.3390/biom11111666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615858/
https://www.ncbi.nlm.nih.gov/pubmed/34827664
http://dx.doi.org/10.3390/biom11111666

Ejemplares similares