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An Asp to Strike Out Cancer? Therapeutic Possibilities Arising from Aspartate’s Emerging Roles in Cell Proliferation and Survival
A better understanding of the metabolic constraints of a tumor may lead to more effective anticancer treatments. Evidence has emerged in recent years shedding light on a crucial aspartate dependency of many tumor types. As a precursor for nucleotide synthesis, aspartate is indispensable for cell pro...
Autores principales: | Helenius, Iiro Taneli, Madala, Hanumantha Rao, Yeh, Jing-Ruey Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615858/ https://www.ncbi.nlm.nih.gov/pubmed/34827664 http://dx.doi.org/10.3390/biom11111666 |
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