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Verification of Blood-Brain Barrier Disruption Based on the Clinical Validation Platform Using a Rat Model with Human Skull

Methods to improve drug delivery efficiency through blood-brain barrier disruption (BBBD) based on microbubbles and focused ultrasound (FUS) are continuously being studied. However, most studies are being conducted in preclinical trial environments using small animals. The use of the human skull sho...

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Detalles Bibliográficos
Autores principales: Park, Chan Yuk, Seo, Hyeon, Lee, Eun-Hee, Han, Mun, Choi, Hyojin, Park, Ki-Su, Yoon, Sang-Youl, Chang, Sung Hyun, Park, Juyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615862/
https://www.ncbi.nlm.nih.gov/pubmed/34827428
http://dx.doi.org/10.3390/brainsci11111429