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Macroautophagy and Mitophagy in Neurodegenerative Disorders: Focus on Therapeutic Interventions
Macroautophagy, a quality control mechanism, is an evolutionarily conserved pathway of lysosomal degradation of protein aggregates, pathogens, and damaged organelles. As part of its vital homeostatic role, macroautophagy deregulation is associated with various human disorders, including neurodegener...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615936/ https://www.ncbi.nlm.nih.gov/pubmed/34829854 http://dx.doi.org/10.3390/biomedicines9111625 |