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Macroautophagy and Mitophagy in Neurodegenerative Disorders: Focus on Therapeutic Interventions

Macroautophagy, a quality control mechanism, is an evolutionarily conserved pathway of lysosomal degradation of protein aggregates, pathogens, and damaged organelles. As part of its vital homeostatic role, macroautophagy deregulation is associated with various human disorders, including neurodegener...

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Detalles Bibliográficos
Autores principales: Magalhães, João Duarte, Fão, Lígia, Vilaça, Rita, Cardoso, Sandra Morais, Rego, Ana Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615936/
https://www.ncbi.nlm.nih.gov/pubmed/34829854
http://dx.doi.org/10.3390/biomedicines9111625