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Gossypol Acetic Acid Attenuates Cardiac Ischemia/Reperfusion Injury in Rats via an Antiferroptotic Mechanism

Myocardial ischemia/reperfusion (I/R) injury has been associated with ferroptosis, which is characterized by an iron-dependent accumulation of lipid peroxide to lethal levels. Gossypol acetic acid (GAA), a natural product taken from the seeds of cotton plants, prevents oxidative stress. However, the...

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Detalles Bibliográficos
Autores principales: Lin, Jian-Hong, Yang, Kun-Ta, Ting, Pei-Ching, Luo, Yu-Po, Lin, Ding-Jyun, Wang, Yi-Shun, Chang, Jui-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615989/
https://www.ncbi.nlm.nih.gov/pubmed/34827665
http://dx.doi.org/10.3390/biom11111667