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PGRMC1 Promotes Progestin-Dependent Proliferation of Breast Cancer Cells by Binding Prohibitins Resulting in Activation of ERα Signaling

SIMPLE SUMMARY: Combined menopausal hormone therapy is associated with increased breast cancer risk in postmenopausal women. In our previous studies, progesterone receptor membrane component 1 (PGRMC1) was shown to play a role in progestins’ elicitation of enhanced proliferation of breast cancer cel...

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Detalles Bibliográficos
Autores principales: Bai, Yingxue, Ludescher, Marina, Poschmann, Gereon, Stühler, Kai, Wyrich, Martine, Oles, Julia, Franken, André, Rivandi, Mahdi, Abramova, Anna, Reinhardt, Florian, Ruckhäberle, Eugen, Niederacher, Dieter, Fehm, Tanja, Cahill, Michael A., Stamm, Nadia, Neubauer, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8615993/
https://www.ncbi.nlm.nih.gov/pubmed/34830790
http://dx.doi.org/10.3390/cancers13225635