Nitric Oxide Mediation in Hydroxyurea and Nitric Oxide Metabolites’ Inhibition of Erythroid Progenitor Growth

In several systems, hydroxyurea has been shown to trigger nitric oxide (NO) release or activation of NO synthase (NOS). To elucidate this duality in its pharmacological effects, during myelosuppression, we individually examined hydroxyurea’s (NO releasing agent) and NO metabolites’ (stable NO degrad...

Descripción completa

Detalles Bibliográficos
Autores principales: Subotički, Tijana, Mitrović Ajtić, Olivera, Djikić, Dragoslava, Kovačić, Marijana, Santibanez, Juan F., Tošić, Milica, Čokić, Vladan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616001/
https://www.ncbi.nlm.nih.gov/pubmed/34827560
http://dx.doi.org/10.3390/biom11111562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616001/
https://www.ncbi.nlm.nih.gov/pubmed/34827560
http://dx.doi.org/10.3390/biom11111562

Ejemplares similares