Interaction of the Escherichia coli HU Protein with Various Topological Forms of DNA

E. coli histone-like protein HU has been shown to interact with different topological forms of DNA. Using radiolabeled HU, we examine the effects of DNA supercoiling on HU–DNA interactions. We show that HU binds preferentially to negatively supercoiled DNA and that the affinity of HU for DNA increas...

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Detalles Bibliográficos
Autores principales: Huang, Li, Zhang, Zhenfeng, McMacken, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616027/
https://www.ncbi.nlm.nih.gov/pubmed/34827722
http://dx.doi.org/10.3390/biom11111724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616027/
https://www.ncbi.nlm.nih.gov/pubmed/34827722
http://dx.doi.org/10.3390/biom11111724

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