Universal Germline Testing of Unselected Cancer Patients Detects Pathogenic Variants Missed by Standard Guidelines without Increasing Healthcare Costs

SIMPLE SUMMARY: Clinical genetic testing likely underestimates the frequency of pathogenic germline variants (PGVs) in a cancer patient population due to strict qualifications designated by practice guidelines. Accurate ascertainment of PGVs in cancer patients can be paramount to the treatment of he...

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Detalles Bibliográficos
Autores principales: Perkins, Adrienne T., Haslem, Derrick, Goldsberry, Jessica, Shortt, Katherine, Sittig, Laura, Raghunath, Sharanya, Giauque, Christopher, Snow, Shawnee, Fulde, Gail, Moulton, Bryce, Jones, David, Nadauld, Lincoln
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616044/
https://www.ncbi.nlm.nih.gov/pubmed/34830767
http://dx.doi.org/10.3390/cancers13225612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616044/
https://www.ncbi.nlm.nih.gov/pubmed/34830767
http://dx.doi.org/10.3390/cancers13225612

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