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Universal Germline Testing of Unselected Cancer Patients Detects Pathogenic Variants Missed by Standard Guidelines without Increasing Healthcare Costs

SIMPLE SUMMARY: Clinical genetic testing likely underestimates the frequency of pathogenic germline variants (PGVs) in a cancer patient population due to strict qualifications designated by practice guidelines. Accurate ascertainment of PGVs in cancer patients can be paramount to the treatment of he...

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Detalles Bibliográficos
Autores principales:	Perkins, Adrienne T., Haslem, Derrick, Goldsberry, Jessica, Shortt, Katherine, Sittig, Laura, Raghunath, Sharanya, Giauque, Christopher, Snow, Shawnee, Fulde, Gail, Moulton, Bryce, Jones, David, Nadauld, Lincoln
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616044/ https://www.ncbi.nlm.nih.gov/pubmed/34830767 http://dx.doi.org/10.3390/cancers13225612

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