MAPK Inhibition Requires Active RAC1 Signaling to Effectively Improve Iodide Uptake by Thyroid Follicular Cells

SIMPLE SUMMARY: The Sodium/Iodide Simulator (NIS) is responsible for the uptake of iodide in the thyroid follicular cells. NIS is present in most differentiated thyroid carcinomas (DTC), allowing radioactive iodine (RAI) to be used to destroy malignant cells. However, a significant proportion of DTC...

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Detalles Bibliográficos
Autores principales: Faria, Márcia, Domingues, Rita, Bugalho, Maria João, Matos, Paulo, Silva, Ana Luísa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616057/
https://www.ncbi.nlm.nih.gov/pubmed/34831012
http://dx.doi.org/10.3390/cancers13225861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616057/
https://www.ncbi.nlm.nih.gov/pubmed/34831012
http://dx.doi.org/10.3390/cancers13225861

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