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MAPK Inhibition Requires Active RAC1 Signaling to Effectively Improve Iodide Uptake by Thyroid Follicular Cells
SIMPLE SUMMARY: The Sodium/Iodide Simulator (NIS) is responsible for the uptake of iodide in the thyroid follicular cells. NIS is present in most differentiated thyroid carcinomas (DTC), allowing radioactive iodine (RAI) to be used to destroy malignant cells. However, a significant proportion of DTC...
Autores principales: | Faria, Márcia, Domingues, Rita, Bugalho, Maria João, Matos, Paulo, Silva, Ana Luísa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616057/ https://www.ncbi.nlm.nih.gov/pubmed/34831012 http://dx.doi.org/10.3390/cancers13225861 |
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