Canonical and Non-Canonical Roles of PFKFB3 in Brain Tumors

PFKFB3 is a bifunctional enzyme that modulates and maintains the intracellular concentrations of fructose-2,6-bisphosphate (F2,6-P2), essentially controlling the rate of glycolysis. PFKFB3 is a known activator of glycolytic rewiring in neoplastic cells, including central nervous system (CNS) neoplas...

Descripción completa

Detalles Bibliográficos
Autores principales: Alvarez, Reinier, Mandal, Debjani, Chittiboina, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616071/
https://www.ncbi.nlm.nih.gov/pubmed/34831136
http://dx.doi.org/10.3390/cells10112913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616071/
https://www.ncbi.nlm.nih.gov/pubmed/34831136
http://dx.doi.org/10.3390/cells10112913

Ejemplares similares