miR-1227 Targets SEC23A to Regulate the Shedding of Large Extracellular Vesicles

SIMPLE SUMMARY: Extracellular vesicles (EVs) are heterogenous in size, cargo, and mechanism of biogenesis. While the mechanism of formation of small EVs, such as exosomes, has been widely investigated, little is known about the pathobiology of large EVs. We identify here a microRNA that alters cellu...

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Detalles Bibliográficos
Autores principales: Chin, Andrew, Mariscal, Javier, Kim, Minhyung, Guerra, Giorgia, Victor, Blandine, Qian, Chen, Broseghini, Elisabetta, Posadas, Edwin, Freeman, Michael R., Sharma, Shivani, Gandellini, Paolo, Zaffaroni, Nadia, You, Sungyong, Chan, Keith Syson, Guarnerio, Jlenia, Fabbri, Muller, Di Vizio, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616086/
https://www.ncbi.nlm.nih.gov/pubmed/34831007
http://dx.doi.org/10.3390/cancers13225850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616086/
https://www.ncbi.nlm.nih.gov/pubmed/34831007
http://dx.doi.org/10.3390/cancers13225850

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