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Altered Mucus Barrier Integrity and Increased Susceptibility to Colitis in Mice upon Loss of Telocyte Bone Morphogenetic Protein Signalling
FoxL1(+)-Telocytes (TC(FoxL1+)) are subepithelial cells that form a network underneath the epithelium. We have shown that without inflammatory stress, mice with loss of function in the BMP signalling pathway in TC(FoxL1+) (BmpR1a(ΔFoxL1+)) initiated colonic neoplasia. Although TC(FoxL1+) are modulat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616098/ https://www.ncbi.nlm.nih.gov/pubmed/34831177 http://dx.doi.org/10.3390/cells10112954 |