Altered Mucus Barrier Integrity and Increased Susceptibility to Colitis in Mice upon Loss of Telocyte Bone Morphogenetic Protein Signalling

FoxL1(+)-Telocytes (TC(FoxL1+)) are subepithelial cells that form a network underneath the epithelium. We have shown that without inflammatory stress, mice with loss of function in the BMP signalling pathway in TC(FoxL1+) (BmpR1a(ΔFoxL1+)) initiated colonic neoplasia. Although TC(FoxL1+) are modulat...

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Detalles Bibliográficos
Autores principales: Reyes Nicolás, Vilcy, Allaire, Joannie M., Alfonso, Alain B., Pupo Gómez, Dianne, Pomerleau, Véronique, Giroux, Véronique, Boudreau, François, Perreault, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616098/
https://www.ncbi.nlm.nih.gov/pubmed/34831177
http://dx.doi.org/10.3390/cells10112954

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