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Accumulation of Paneth Cells in Early Colorectal Adenomas Is Associated with Beta-Catenin Signaling and Poor Patient Prognosis

Background: Previous studies in mice indicated that Paneth cells and c-Kit-positive goblet cells represent the stem cell niche of the small intestine and colon, respectively, partly by supporting Wnt and Notch activation. Whether these cell populations play a similar role in human intestinal cancer...

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Detalles Bibliográficos
Autores principales: López-Arribillaga, Erika, Yan, Bing, Lobo-Jarne, Teresa, Guillén, Yolanda, Menéndez, Silvia, Andreu, Montserrat, Bigas, Anna, Iglesias, Mar, Espinosa, Lluís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616107/
https://www.ncbi.nlm.nih.gov/pubmed/34831152
http://dx.doi.org/10.3390/cells10112928