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Silencing of the ER and Integrative Stress Responses in the Liver of Mice with Error-Prone Translation

Translational errors frequently arise during protein synthesis, producing misfolded and dysfunctional proteins. Chronic stress resulting from translation errors may be particularly relevant in tissues that must synthesize and secrete large amounts of secretory proteins. Here, we studied the proteost...

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Detalles Bibliográficos
Autores principales: Moore, James, Osinnii, Ivan, Grimm, Amandine, Oettinghaus, Björn, Eckert, Anne, Frank, Stephan, Böttger, Erik C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616113/
https://www.ncbi.nlm.nih.gov/pubmed/34831079
http://dx.doi.org/10.3390/cells10112856