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Dysregulation of Cytoskeleton Remodeling Drives Invasive Leading Cells Detachment

SIMPLE SUMMARY: Detachment of cancer cells is the first step in tumor metastasis and malignancy. Our results showed that the TGF-β1/vimentin/focal adhesion protein assembly axis was involved in the control of the dynamics of initial tumor detachment under adequate nutrition, based on the Boyden cham...

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Detalles Bibliográficos
Autores principales: Peng, Jei-Ming, Chen, Wei-Yu, Cheng, Jai-Hong, Luo, Jia-Wun, Tzeng, Hong-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616115/
https://www.ncbi.nlm.nih.gov/pubmed/34830801
http://dx.doi.org/10.3390/cancers13225648