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Deletion or Inhibition of Astrocytic Transglutaminase 2 Promotes Functional Recovery after Spinal Cord Injury

Following CNS injury, astrocytes become “reactive” and exhibit pro-regenerative or harmful properties. However, the molecular mechanisms that cause astrocytes to adopt either phenotype are not well understood. Transglutaminase 2 (TG2) plays a key role in regulating the response of astrocytes to insu...

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Detalles Bibliográficos
Autores principales: Elahi, Anissa, Emerson, Jacen, Rudlong, Jacob, Keillor, Jeffrey W., Salois, Garrick, Visca, Adam, Girardi, Peter, Johnson, Gail V.W., Pröschel, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616117/
https://www.ncbi.nlm.nih.gov/pubmed/34831164
http://dx.doi.org/10.3390/cells10112942