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Experimental Epileptogenesis in a Cell Culture Model of Primary Neurons from Rat Brain: A Temporal Multi-Scale Study

Understanding seizure development requires an integrated knowledge of different scales of organization of epileptic networks. We developed a model of “epilepsy-in-a-dish” based on dissociated primary neuronal cells from neonatal rat hippocampus. We demonstrate how a single application of glutamate s...

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Detalles Bibliográficos
Autores principales: Jablonski, Janos, Hoffmann, Lucas, Blümcke, Ingmar, Fejtová, Anna, Uebe, Steffen, Ekici, Arif B., Gnatkovsky, Vadym, Kobow, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616120/
https://www.ncbi.nlm.nih.gov/pubmed/34831225
http://dx.doi.org/10.3390/cells10113004