FGFR1 Overexpression Induces Cancer Cell Stemness and Enhanced Akt/Erk-ER Signaling to Promote Palbociclib Resistance in Luminal A Breast Cancer Cells

Resistance to CDK4/6 inhibitors (CDKis) is emerging as a clinical challenge. Identification of the factors contributing to CDKi resistance, with mechanistic insight, is of pivotal significance. Recent studies linked aberrant FGFR signaling to CDKi resistance. However, detailed mechanisms are less cl...

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Detalles Bibliográficos
Autores principales: Cheng, Qiong, Ma, Zhikun, Shi, Yujie, Parris, Amanda B., Kong, Lingfei, Yang, Xiaohe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616148/
https://www.ncbi.nlm.nih.gov/pubmed/34831231
http://dx.doi.org/10.3390/cells10113008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616148/
https://www.ncbi.nlm.nih.gov/pubmed/34831231
http://dx.doi.org/10.3390/cells10113008

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