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Abnormal Calcium Handling in Atrial Fibrillation Is Linked to Changes in Cyclic AMP Dependent Signaling

Both, the decreased L-type Ca(2+) current (I(Ca,L)) density and increased spontaneous Ca(2+) release from the sarcoplasmic reticulum (SR), have been associated with atrial fibrillation (AF). In this study, we tested the hypothesis that remodeling of 3′,5′-cyclic adenosine monophosphate (cAMP)-depend...

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Detalles Bibliográficos
Autores principales: Reinhardt, Franziska, Beneke, Kira, Pavlidou, Nefeli Grammatica, Conradi, Lenard, Reichenspurner, Hermann, Hove-Madsen, Leif, Molina, Cristina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616167/
https://www.ncbi.nlm.nih.gov/pubmed/34831263
http://dx.doi.org/10.3390/cells10113042