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Impact of SOCE Abolition by ORAI1 Knockout on the Proliferation, Adhesion, and Migration of HEK-293 Cells

Store-operated calcium entry (SOCE) provided through channels formed by ORAI proteins is a major regulator of several cellular processes. In immune cells, it controls fundamental processes such as proliferation, cell adhesion, and migration, while in cancer, SOCE and ORAI1 gene expression are dysreg...

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Detalles Bibliográficos
Autores principales: Bokhobza, Alexandre, Ziental-Gelus, Nathalie, Allart, Laurent, Iamshanova, Oksana, Vanden Abeele, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616168/
https://www.ncbi.nlm.nih.gov/pubmed/34831241
http://dx.doi.org/10.3390/cells10113016