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Oncogenic KRAS: Signaling and Drug Resistance

SIMPLE SUMMARY: KRAS is one of the oncogenic proteins and best well-known GTPase proteins. Although KRAS serves as regulation of cellular process, abnormal mutated and GTP-bound KRAS is highly expressed in human cancers. Understanding biological characteristics and precise signaling of KRAS proteins...

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Detalles Bibliográficos
Autores principales: Kim, Hyeon Jin, Lee, Han Na, Jeong, Mi Suk, Jang, Se Bok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616169/
https://www.ncbi.nlm.nih.gov/pubmed/34830757
http://dx.doi.org/10.3390/cancers13225599