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25-Hydroxycholesterol 3-Sulfate Recovers Acetaminophen Induced Acute Liver Injury via Stabilizing Mitochondria in Mouse Models

Acetaminophen (APAP) overdose is one of the most frequent causes of acute liver failure (ALF). N-acetylcysteine (NAC) is currently being used as part of the standard care in the clinic but its usage has been limited in severe cases, in which liver transplantation becomes the only treatment option. T...

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Detalles Bibliográficos
Autores principales: Wang, Yaping, Pandak, William M., Lesnefsky, Edward J., Hylemon, Phillip B., Ren, Shunlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616185/
https://www.ncbi.nlm.nih.gov/pubmed/34831255
http://dx.doi.org/10.3390/cells10113027