IPF-Fibroblast Erk1/2 Activity Is Independent from microRNA Cluster 17-92 but Can Be Inhibited by Treprostinil through DUSP1

Idiopathic pulmonary fibrosis (IPF) is a progressive terminal lung disease, and therapies aim to block fibrosis. Fibroblast proliferation is controlled by C/EBP-β, microRNA cluster 17-92 (miR17-92), and Erk1/2 mitogen-activated protein kinase. This study assessed the role of miR17-92 in IPF-fibrobla...

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Detalles Bibliográficos
Autores principales: Blumer, Sabrina, Fang, Lei, Chen, Wei-Chih, Khan, Petra, Hostettler, Katrin, Tamm, Michael, Roth, Michael, Lambers, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616195/
https://www.ncbi.nlm.nih.gov/pubmed/34831059
http://dx.doi.org/10.3390/cells10112836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616195/
https://www.ncbi.nlm.nih.gov/pubmed/34831059
http://dx.doi.org/10.3390/cells10112836

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