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Immunosuppressive Microenvironment and Efficacy of PD-1 Inhibitors in Relapsed/Refractory Classic Hodgkin Lymphoma: Checkpoint Molecules Landscape and Macrophage Populations

SIMPLE SUMMARY: Classic Hodgkin lymphoma contains rare malignant Hodgkin/Reed–Sternberg cells and abundant reactive populations in the tumor microenvironment. Many aspects of the interaction between tumor cells and immune cells remain unclear. Nevertheless, the microenvironment is believed to play a...

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Detalles Bibliográficos
Autores principales: Gusak, Artem, Fedorova, Liudmila, Lepik, Kirill, Volkov, Nikita, Popova, Marina, Moiseev, Ivan, Mikhailova, Natalia, Baykov, Vadim, Kulagin, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616219/
https://www.ncbi.nlm.nih.gov/pubmed/34830831
http://dx.doi.org/10.3390/cancers13225676