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High Grade of Amplification of Six Regions on Chromosome 2p in a Neuroblastoma Patient with Very Poor Outcome: The Putative New Oncogene TSSC1

SIMPLE SUMMARY: Here, a case of neuroblastoma (NB) carrying a high-grade amplification of six loci besides MYCN is described. Since the patient had a very poor outcome, we postulated that these DNA co-amplifications might have a synergistic effect in increasing NB cell proliferation. In order to ver...

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Detalles Bibliográficos
Autores principales: Ognibene, Marzia, Amoroso, Loredana, Melchionda, Fraia, Cangelosi, Davide, Zara, Federico, Parodi, Stefano, Pezzolo, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616235/
https://www.ncbi.nlm.nih.gov/pubmed/34830942
http://dx.doi.org/10.3390/cancers13225792