Functional Inhibition of Valosin-Containing Protein Induces Cardiac Dilation and Dysfunction in a New Dominant-Negative Transgenic Mouse Model

Valosin-containing protein (VCP) was found to play a vital protective role against cardiac stresses. Genetic mutations of VCP are associated with human dilated cardiomyopathy. However, the essential role of VCP in the heart during the physiological condition remains unknown since the VCP knockout in...

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Detalles Bibliográficos
Autores principales: Sun, Xiaonan, Zhou, Ning, Ma, Ben, Wu, Wenqian, Stoll, Shaunrick, Lai, Lo, Qin, Gangjian, Qiu, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616236/
https://www.ncbi.nlm.nih.gov/pubmed/34831118
http://dx.doi.org/10.3390/cells10112891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616236/
https://www.ncbi.nlm.nih.gov/pubmed/34831118
http://dx.doi.org/10.3390/cells10112891

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