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Prognostic Values of G-Protein Mutations in Metastatic Uveal Melanoma

SIMPLE SUMMARY: Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. More than 90% of UMs harbor mutually exclusive activating mutations in G-proteins. The mutations are early events in UM development and considered to be driver mutations in carcinogenesis. Even after tre...

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Detalles Bibliográficos
Autores principales: Terai, Mizue, Shimada, Ayako, Chervoneva, Inna, Hulse, Liam, Danielson, Meggie, Swensen, Jeff, Orloff, Marlana, Wedegaertner, Philip B., Benovic, Jeffrey L., Aplin, Andrew E., Sato, Takami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616238/
https://www.ncbi.nlm.nih.gov/pubmed/34830903
http://dx.doi.org/10.3390/cancers13225749