A Targeted Catalytic Nanobody (T-CAN) with Asparaginolytic Activity

SIMPLE SUMMARY: The therapy of Acute Lymphoblastic Leukemia (ALL) is based on Escherichia coli (E. coli) L-asparaginase, which is a very effective drug in most cases. However, its side effects sometimes prevent its usage or impose its interruption. The main issues derive from its bacterial origin, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Maggi, Maristella, Pessino, Greta, Guardamagna, Isabella, Lonati, Leonardo, Pulimeno, Cristina, Scotti, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616244/
https://www.ncbi.nlm.nih.gov/pubmed/34830793
http://dx.doi.org/10.3390/cancers13225637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616244/
https://www.ncbi.nlm.nih.gov/pubmed/34830793
http://dx.doi.org/10.3390/cancers13225637

Ejemplares similares