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A Targeted Catalytic Nanobody (T-CAN) with Asparaginolytic Activity
SIMPLE SUMMARY: The therapy of Acute Lymphoblastic Leukemia (ALL) is based on Escherichia coli (E. coli) L-asparaginase, which is a very effective drug in most cases. However, its side effects sometimes prevent its usage or impose its interruption. The main issues derive from its bacterial origin, w...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616244/ https://www.ncbi.nlm.nih.gov/pubmed/34830793 http://dx.doi.org/10.3390/cancers13225637 |