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Trans-Ned 19-Mediated Antagonism of Nicotinic Acid Adenine Nucleotide—Mediated Calcium Signaling Regulates Th17 Cell Plasticity in Mice

Nicotinic acid adenine dinucleotide phosphate (NAADP) is the most potent Ca(2+) mobilizing agent and its inhibition proved to inhibit T-cell activation. However, the impact of the NAADP signaling on CD4(+) T-cell differentiation and plasticity and on the inflammation in tissues other than the centra...

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Detalles Bibliográficos
Autores principales: Nawrocki, Mikołaj, Lory, Niels, Bedke, Tanja, Stumme, Friederike, Diercks, Björn-Phillip, Guse, Andreas H., Meier, Chris, Gagliani, Nicola, Mittrücker, Hans-Willi, Huber, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616272/
https://www.ncbi.nlm.nih.gov/pubmed/34831261
http://dx.doi.org/10.3390/cells10113039