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Trans-Ned 19-Mediated Antagonism of Nicotinic Acid Adenine Nucleotide—Mediated Calcium Signaling Regulates Th17 Cell Plasticity in Mice
Nicotinic acid adenine dinucleotide phosphate (NAADP) is the most potent Ca(2+) mobilizing agent and its inhibition proved to inhibit T-cell activation. However, the impact of the NAADP signaling on CD4(+) T-cell differentiation and plasticity and on the inflammation in tissues other than the centra...
Autores principales: | Nawrocki, Mikołaj, Lory, Niels, Bedke, Tanja, Stumme, Friederike, Diercks, Björn-Phillip, Guse, Andreas H., Meier, Chris, Gagliani, Nicola, Mittrücker, Hans-Willi, Huber, Samuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616272/ https://www.ncbi.nlm.nih.gov/pubmed/34831261 http://dx.doi.org/10.3390/cells10113039 |
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