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Inhibition of Vasculogenic Mimicry and Angiogenesis by an Anti-EGFR IgG1-Human Endostatin-P125A Fusion Protein Reduces Triple Negative Breast Cancer Metastases

Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype with limited therapeutic options. Metastasis is the major cause of TNBC mortality. Angiogenesis facilitates TNBC metastases. Many TNBCs also form vascular channels lined by tumor cells rather than endothelial cells, known as...

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Detalles Bibliográficos
Autores principales: Shin, Seung-Uon, Cho, Hyun-Mi, Das, Rathin, Gil-Henn, Hava, Ramakrishnan, Sundaram, Al Bayati, Ahmed, Carroll, Stephen F., Zhang, Yu, Sankar, Ankita P., Elledge, Christian, Pimentel, Augustin, Blonska, Marzenna, Rosenblatt, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616280/
https://www.ncbi.nlm.nih.gov/pubmed/34831127
http://dx.doi.org/10.3390/cells10112904