Cyclin E1 in Murine and Human Liver Cancer: A Promising Target for Therapeutic Intervention during Tumour Progression

SIMPLE SUMMARY: The cell cycle regulator Cyclin E1 is a key mediator and biomarker of liver cancer progression in mice and man independent of its canonical interacting partner Cyclin-dependent kinase 2. Over-expression of Cyclin E1 during hepatocarcinogenesis modulates several distinct biological pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Sonntag, Roland, Penners, Christian, Kohlhepp, Marlene, Haas, Ute, Lambertz, Daniela, Kroh, Andreas, Cramer, Thorsten, Ticconi, Fabio, Costa, Ivan G., Tacke, Frank, Gassler, Nikolaus, Trautwein, Christian, Liedtke, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616292/
https://www.ncbi.nlm.nih.gov/pubmed/34830835
http://dx.doi.org/10.3390/cancers13225680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616292/
https://www.ncbi.nlm.nih.gov/pubmed/34830835
http://dx.doi.org/10.3390/cancers13225680

Ejemplares similares