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Low-Dose Pesticides Alter Primary Human Bone Marrow Mesenchymal Stem/Stromal Cells through ALDH2 Inhibition

SIMPLE SUMMARY: Pesticide exposure is a public health concern. Two recent studies reported that exposure of normal primary bone marrow mesenchymal stem/stromal cells (BM-MSCs) to low-dose pesticide mixture induces deleterious consequences, such as oxidative stress, senescence, accelerated aging and...

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Detalles Bibliográficos
Autores principales: Foucault, Amélie, Ravalet, Noémie, Besombes, Joevin, Picou, Frédéric, Gallay, Nathalie, Babin, Laetitia, Bourgeais, Jérôme, Hamard, Sophie, Domenech, Jorge, Loyer, Pascal, Vallet, Nicolas, Lejeune, Julien, Gyan, Emmanuel, Béné, Marie C., Vallette, François, Olivier, Christophe, Hérault, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616329/
https://www.ncbi.nlm.nih.gov/pubmed/34830855
http://dx.doi.org/10.3390/cancers13225699