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The Release of Inflammatory Mediators from Acid-Stimulated Mesenchymal Stromal Cells Favours Tumour Invasiveness and Metastasis in Osteosarcoma

SIMPLE SUMMARY: We aimed to validate the correlation between tumour glycolysis/acidosis and inflammation in osteosarcoma-associated mesenchymal stromal cells and investigate the role of acidity-induced inflammation in the development of metastasis in this very aggressive cancer. We confirmed the pre...

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Detalles Bibliográficos
Autores principales: Avnet, Sofia, Lemma, Silvia, Cortini, Margherita, Di Pompo, Gemma, Perut, Francesca, Lipreri, Maria Veronica, Roncuzzi, Laura, Columbaro, Marta, Errani, Costantino, Longhi, Alessandra, Zini, Nicoletta, Heymann, Dominique, Dominici, Massimo, Grisendi, Giulia, Golinelli, Giulia, Consolino, Lorena, Longo, Dario Livio, Nanni, Cristina, Righi, Alberto, Baldini, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616358/
https://www.ncbi.nlm.nih.gov/pubmed/34831016
http://dx.doi.org/10.3390/cancers13225855