Functional Recellularization of Acellular Rat Liver Scaffold by Induced Pluripotent Stem Cells: Molecular Evidence for Wnt/B-Catenin Upregulation

Background. Liver transplantation remains the only viable therapy for liver failure but has a severely restricted utility. Here, we aimed to decellularize rat livers to form acellular 3D bio-scaffolds suitable for seeding with induced pluripotent cells (iPSCs) as a tool to investigate the role of Wn...

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Detalles Bibliográficos
Autores principales: Ebrahim, Nesrine, Badr, Omnia A. M., Yousef, Mohamed M., Hassouna, Amira, Sabry, Dina, Farid, Ayman Samir, Mostafa, Ola, Saihati, Hajir A. Al, Seleem, Yasmin, Abd El Aziz, Eman, Khalil, Ahmed Hassan, Nawar, Ahmed, Shoulah, Ahmed A., Aljasir, Mohammad, Mohamed, Amira Zaki, El-Sherbiny, Mohamed, Elsherbiny, Nehal M., Eladl, Mohamed Ahmed, Forsyth, Nicholas Robert, Salim, Rabab F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616374/
https://www.ncbi.nlm.nih.gov/pubmed/34831042
http://dx.doi.org/10.3390/cells10112819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616374/
https://www.ncbi.nlm.nih.gov/pubmed/34831042
http://dx.doi.org/10.3390/cells10112819

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