Differential Stimulation of Pluripotent Stem Cell-Derived Human Microglia Leads to Exosomal Proteomic Changes Affecting Neurons

Microglial exosomes are an emerging communication pathway, implicated in fulfilling homeostatic microglial functions and transmitting neurodegenerative signals. Gene variants of triggering receptor expressed on myeloid cells-2 (TREM2) are associated with an increased risk of developing dementia. We...

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Detalles Bibliográficos
Autores principales: Mallach, Anna, Gobom, Johan, Arber, Charles, Piers, Thomas M., Hardy, John, Wray, Selina, Zetterberg, Henrik, Pocock, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616378/
https://www.ncbi.nlm.nih.gov/pubmed/34831089
http://dx.doi.org/10.3390/cells10112866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616378/
https://www.ncbi.nlm.nih.gov/pubmed/34831089
http://dx.doi.org/10.3390/cells10112866

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