Drosophila Nesprin-1 Isoforms Differentially Contribute to Muscle Function

Nesprin-1 is a large scaffold protein connecting nuclei to the actin cytoskeleton via its KASH and Calponin Homology domains, respectively. Nesprin-1 disconnection from nuclei results in altered muscle function and myonuclei mispositioning. Furthermore, Nesprin-1 mutations are associated with muscul...

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Detalles Bibliográficos
Autores principales: Rey, Alexandre, Schaeffer, Laurent, Durand, Bénédicte, Morel, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616381/
https://www.ncbi.nlm.nih.gov/pubmed/34831284
http://dx.doi.org/10.3390/cells10113061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616381/
https://www.ncbi.nlm.nih.gov/pubmed/34831284
http://dx.doi.org/10.3390/cells10113061

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