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Molecular Mechanisms of mtDNA-Mediated Inflammation

Besides their role in cell metabolism, mitochondria display many other functions. Mitochondrial DNA (mtDNA), the own genome of the organelle, plays an important role in modulating the inflammatory immune response. When released from the mitochondrion to the cytosol, mtDNA is recognized by cGAS, a cG...

תיאור מלא

מידע ביבליוגרפי
Autores principales: De Gaetano, Anna, Solodka, Kateryna, Zanini, Giada, Selleri, Valentina, Mattioli, Anna Vittoria, Nasi, Milena, Pinti, Marcello
פורמט: Online Artículo Texto
שפה:English
יצא לאור: MDPI 2021
נושאים:
גישה מקוונת:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616383/
https://www.ncbi.nlm.nih.gov/pubmed/34831121
http://dx.doi.org/10.3390/cells10112898