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Molecular Mechanisms of mtDNA-Mediated Inflammation

Besides their role in cell metabolism, mitochondria display many other functions. Mitochondrial DNA (mtDNA), the own genome of the organelle, plays an important role in modulating the inflammatory immune response. When released from the mitochondrion to the cytosol, mtDNA is recognized by cGAS, a cG...

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Detalles Bibliográficos
Autores principales:	De Gaetano, Anna, Solodka, Kateryna, Zanini, Giada, Selleri, Valentina, Mattioli, Anna Vittoria, Nasi, Milena, Pinti, Marcello
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616383/ https://www.ncbi.nlm.nih.gov/pubmed/34831121 http://dx.doi.org/10.3390/cells10112898

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