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Transcriptional and Metabolic Investigation in 5′-Nucleotidase Deficient Cancer Cell Lines

Enzymes of nucleoside and nucleotide metabolism regulate important cellular processes with potential impacts on nucleotide-unrelated parameters. We have used a set of CRISPR/Cas9-modified cell models expressing both, one, or none of the 5′-nucleotidases cN-II and CD73, together with RNA sequencing a...

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Detalles Bibliográficos
Autores principales: Cadassou, Octavia, Forey, Prescillia, Machon, Christelle, Petrotto, Edoardo, Chettab, Kamel, Tozzi, Maria Grazia, Guitton, Jérôme, Dumontet, Charles, Cros-Perrial, Emeline, Jordheim, Lars Petter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616413/
https://www.ncbi.nlm.nih.gov/pubmed/34831141
http://dx.doi.org/10.3390/cells10112918