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The Transcription Factor FEZF1, a Direct Target of EWSR1-FLI1 in Ewing Sarcoma Cells, Regulates the Expression of Neural-Specific Genes

SIMPLE SUMMARY: Ewing sarcoma is a rare pediatric tumor characterized by chromosomal translocations that give rise to aberrant chimeric transcription factors (e.g., EWSR1-FLI1). EWSR1-FLI1 defines a specific transcriptomic profile in Ewing sarcoma cells, which determines the tumorigenesis process. O...

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Detalles Bibliográficos
Autores principales: García-García, Laura, Fernández-Tabanera, Enrique, Cervera, Saint T., Melero-Fernández de Mera, Raquel M., Josa, Santiago, González-González, Laura, Rodríguez-Martín, Carlos, Grünewald, Thomas G. P., Alonso, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616448/
https://www.ncbi.nlm.nih.gov/pubmed/34830820
http://dx.doi.org/10.3390/cancers13225668