Pulmonary Alveolar Stem Cell Senescence, Apoptosis, and Differentiation by p53-Dependent and -Independent Mechanisms in Telomerase-Deficient Mice

Pulmonary premature ageing and fibrogenesis as in idiopathic pulmonary fibrosis (IPF) occur with the DNA damage response in lungs deficient of telomerase. The molecular mechanism mediating pulmonary alveolar cell fates remains to be investigated. The present study shows that naturally occurring agei...

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Detalles Bibliográficos
Autores principales: Zhang, Kexiong, Wang, Lihui, Hong, Xiaojing, Chen, Hao, Shi, Yao, Liu, Yingying, Liu, Jun, Liu, Jun-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616483/
https://www.ncbi.nlm.nih.gov/pubmed/34831112
http://dx.doi.org/10.3390/cells10112892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8616483/
https://www.ncbi.nlm.nih.gov/pubmed/34831112
http://dx.doi.org/10.3390/cells10112892

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